null

SMILES: CC(C)CC(=O)NC1CCN(CC1)c1ncnc2n(c(nc12)-c1ccccc1Cl)-c1ccc(Cl)cc1

InChI Key: InChIKey=NZWOCSBGLXYKQK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 192535   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM192535 (US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...) Show SMILES CC(C)CC(=O)NC1CCN(CC1)c1ncnc2n(c(nc12)-c1ccccc1Cl)-c1ccc(Cl)cc1 Show InChI InChI=1S/C27H28Cl2N6O/c1-17(2)15-23(36)32-19-11-13-34(14-12-19)26-24-27(31-16-30-26)35(20-9-7-18(28)8-10-20)25(33-24)21-5-3-4-6-22(21)29/h3-10,16-17,19H,11-15H2,1-2H3,(H,32,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cells				J Med Chem 56: 8066-72 (2013) Article DOI: 10.1021/jm401129n BindingDB Entry DOI: 10.7270/Q2F192NR
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM192535 (US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...) Show SMILES CC(C)CC(=O)NC1CCN(CC1)c1ncnc2n(c(nc12)-c1ccccc1Cl)-c1ccc(Cl)cc1 Show InChI InChI=1S/C27H28Cl2N6O/c1-17(2)15-23(36)32-19-11-13-34(14-12-19)26-24-27(31-16-30-26)35(20-9-7-18(28)8-10-20)25(33-24)21-5-3-4-6-22(21)29/h3-10,16-17,19H,11-15H2,1-2H3,(H,32,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute US Patent					Assay Description Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...				US Patent US9187480 (2015) BindingDB Entry DOI: 10.7270/Q28051DS
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM192535 (US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...) Show SMILES CC(C)CC(=O)NC1CCN(CC1)c1ncnc2n(c(nc12)-c1ccccc1Cl)-c1ccc(Cl)cc1 Show InChI InChI=1S/C27H28Cl2N6O/c1-17(2)15-23(36)32-19-11-13-34(14-12-19)26-24-27(31-16-30-26)35(20-9-7-18(28)8-10-20)25(33-24)21-5-3-4-6-22(21)29/h3-10,16-17,19H,11-15H2,1-2H3,(H,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	89.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute US Patent					Assay Description Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...				US Patent US9187480 (2015) BindingDB Entry DOI: 10.7270/Q28051DS
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM192535 (US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...) Show SMILES CC(C)CC(=O)NC1CCN(CC1)c1ncnc2n(c(nc12)-c1ccccc1Cl)-c1ccc(Cl)cc1 Show InChI InChI=1S/C27H28Cl2N6O/c1-17(2)15-23(36)32-19-11-13-34(14-12-19)26-24-27(31-16-30-26)35(20-9-7-18(28)8-10-20)25(33-24)21-5-3-4-6-22(21)29/h3-10,16-17,19H,11-15H2,1-2H3,(H,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB2 receptor (unknown origin) expressed in CHO-K1 cells				J Med Chem 56: 8066-72 (2013) Article DOI: 10.1021/jm401129n BindingDB Entry DOI: 10.7270/Q2F192NR
					More data for this Ligand-Target Pair