BDBM192558 US9187486, 20

SMILES: C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1Nc1ncc2ccc(nn12)-c1c(F)cccc1F

InChI Key: InChIKey=BHBIGGOODMPQTA-OIAISFKWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 192558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM192558 (US9187486, 20) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1Nc1ncc2ccc(nn12)-c1c(F)cccc1F |r| Show InChI InChI=1S/C23H23F2N7O/c1-13-11-31(12-17(26)22(13)33)20-7-8-27-10-19(20)29-23-28-9-14-5-6-18(30-32(14)23)21-15(24)3-2-4-16(21)25/h2-10,13,17,22,33H,11-12,26H2,1H3,(H,28,29)/t13-,17+,22+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9187486 (2015) BindingDB Entry DOI: 10.7270/Q24748NM
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM192558 (US9187486, 20) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1Nc1ncc2ccc(nn12)-c1c(F)cccc1F |r| Show InChI InChI=1S/C23H23F2N7O/c1-13-11-31(12-17(26)22(13)33)20-7-8-27-10-19(20)29-23-28-9-14-5-6-18(30-32(14)23)21-15(24)3-2-4-16(21)25/h2-10,13,17,22,33H,11-12,26H2,1H3,(H,28,29)/t13-,17+,22+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9187486 (2015) BindingDB Entry DOI: 10.7270/Q24748NM
					More data for this Ligand-Target Pair