BDBM192695 7-(4-((7-Chloro-1,2,3,4-tetrahydroacridin-9-yl)amino)phenoxy)-4-methyl-2H-chromen-2-one (8l)

SMILES: Cc1cc(=O)oc2cc(Oc3ccc(Nc4c5CCCCc5nc5ccc(Cl)cc45)cc3)ccc12

InChI Key: InChIKey=DIEGSTRUQCROTJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 192695   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Butyrylcholinesterase (BChE) (Equus caballus (Horse))	BDBM192695 (7-(4-((7-Chloro-1,2,3,4-tetrahydroacridin-9-yl)ami...) Show SMILES Cc1cc(=O)oc2cc(Oc3ccc(Nc4c5CCCCc5nc5ccc(Cl)cc45)cc3)ccc12 Show InChI InChI=1S/C29H23ClN2O3/c1-17-14-28(33)35-27-16-21(11-12-22(17)27)34-20-9-7-19(8-10-20)31-29-23-4-2-3-5-25(23)32-26-13-6-18(30)15-24(26)29/h6-16H,2-5H2,1H3,(H,31,32)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	n/a
Tehran University of Medical Sciences					Assay Description In vitro AChEI activity was performed based on the modified Ellman's methodas previously reported by our group using a 96-well plate reader (BioTek E...				Bioorg Chem 67: 84-94 (2016) Article DOI: 10.1016/j.bioorg.2016.06.001 BindingDB Entry DOI: 10.7270/Q2R21066
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM192695 (7-(4-((7-Chloro-1,2,3,4-tetrahydroacridin-9-yl)ami...) Show SMILES Cc1cc(=O)oc2cc(Oc3ccc(Nc4c5CCCCc5nc5ccc(Cl)cc45)cc3)ccc12 Show InChI InChI=1S/C29H23ClN2O3/c1-17-14-28(33)35-27-16-21(11-12-22(17)27)34-20-9-7-19(8-10-20)31-29-23-4-2-3-5-25(23)32-26-13-6-18(30)15-24(26)29/h6-16H,2-5H2,1H3,(H,31,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.08E+4	n/a	n/a	n/a	n/a	8.0	n/a
Tehran University of Medical Sciences					Assay Description In vitro AChEI activity was performed based on the modified Ellman's methodas previously reported by our group using a 96-well plate reader (BioTek E...				Bioorg Chem 67: 84-94 (2016) Article DOI: 10.1016/j.bioorg.2016.06.001 BindingDB Entry DOI: 10.7270/Q2R21066
					More data for this Ligand-Target Pair