BDBM192704 7-(3-(5,6-dichlorobenzo[d]thiazol-2-ylamino)-2-hydroxypropoxy)-4-methyl-2H-chromen-2-one (34)

SMILES: Cc1cc(=O)oc2cc(OCC(O)CNc3nc4cc(Cl)c(Cl)cc4s3)ccc12

InChI Key: InChIKey=ISVNHZIUZQCOTO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192704   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-Lipoxygenase (5-LOX) (Glycine max (Soybean))	BDBM192704 (7-(3-(5,6-dichlorobenzo[d]thiazol-2-ylamino)-2-hyd...) Show SMILES Cc1cc(=O)oc2cc(OCC(O)CNc3nc4cc(Cl)c(Cl)cc4s3)ccc12 Show InChI InChI=1S/C20H16Cl2N2O4S/c1-10-4-19(26)28-17-5-12(2-3-13(10)17)27-9-11(25)8-23-20-24-16-6-14(21)15(22)7-18(16)29-20/h2-7,11,25H,8-9H2,1H3,(H,23,24)	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.5	n/a	n/a	n/a	n/a	9.0	25
Nirma University					Assay Description It is determined by kinetic mode of spectro-photometric determination method,which was performed by recording the rate of change in absorbance at 234...				Bioorg Chem 67: 130-8 (2016) Article DOI: 10.1016/j.bioorg.2016.06.004 BindingDB Entry DOI: 10.7270/Q2M907GG
					More data for this Ligand-Target Pair