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SMILES: CN1CCN(CC1)c1ncc(cn1)-c1cc2c(C)cccc2c(=O)[nH]1

InChI Key: InChIKey=OPXKZINJBAHLNR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192895   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase tankyrase-1 [1068-1325]


(Homo sapiens (Human))		BDBM192895
PNG
(US9193689, IQ-025)
Show SMILES CN1CCN(CC1)c1ncc(cn1)-c1cc2c(C)cccc2c(=O)[nH]1
Show InChI InChI=1S/C19H21N5O/c1-13-4-3-5-15-16(13)10-17(22-18(15)25)14-11-20-19(21-12-14)24-8-6-23(2)7-9-24/h3-5,10-12H,6-9H2,1-2H3,(H,22,25)
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Similars
US Patent
n/an/a 17n/an/an/an/an/an/a



INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (THE)

US Patent


Assay Description
Tankyrase activity was assayed using a 96-well format HT Universal Chemiluminescent PARP Assay Kit (Trevigen, Inc, cat. no. 4676-096-K) according to ...

US Patent US9193689 (2015)


BindingDB Entry DOI: 10.7270/Q29S1PTR
More data for this
Ligand-Target Pair