BDBM192899 US9193689, IQ-003

SMILES: CN1CCN(CC1)c1ccc(cn1)-c1cc2c(C)cccc2c(=O)[nH]1

InChI Key: InChIKey=MENBDHBIZBAFHG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192899   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-1 [1068-1325] (Homo sapiens (Human))	BDBM192899 (US9193689, IQ-003) Show SMILES CN1CCN(CC1)c1ccc(cn1)-c1cc2c(C)cccc2c(=O)[nH]1 Show InChI InChI=1S/C20H22N4O/c1-14-4-3-5-16-17(14)12-18(22-20(16)25)15-6-7-19(21-13-15)24-10-8-23(2)9-11-24/h3-7,12-13H,8-11H2,1-2H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (THE) US Patent					Assay Description Tankyrase activity was assayed using a 96-well format HT Universal Chemiluminescent PARP Assay Kit (Trevigen, Inc, cat. no. 4676-096-K) according to ...				US Patent US9193689 (2015) BindingDB Entry DOI: 10.7270/Q29S1PTR
					More data for this Ligand-Target Pair