BDBM192936 US9193697, A7.25

SMILES: COCCOCC(=O)N1CCC(CC1)c1nc(c(Sc2ccc(Cl)cn2)o1)-c1ccc(cc1)S(C)=O

InChI Key: InChIKey=TVSKGJHDKYXGGH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192936   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM192936 (US9193697, A7.25) Show SMILES COCCOCC(=O)N1CCC(CC1)c1nc(c(Sc2ccc(Cl)cn2)o1)-c1ccc(cc1)S(C)=O Show InChI InChI=1S/C25H28ClN3O5S2/c1-32-13-14-33-16-22(30)29-11-9-18(10-12-29)24-28-23(17-3-6-20(7-4-17)36(2)31)25(34-24)35-21-8-5-19(26)15-27-21/h3-8,15,18H,9-14,16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	525	n/a	n/a	n/a	n/a	n/a	n/a
MERCK SHARP & DOHME CORP. US Patent					Assay Description Enzyme activity was demonstrated in a radioenzymatic test based on measuring the product of hydrolysis (ethanolamine [3]H) of anandamide [ethanolam...				US Patent US9193697 (2015) BindingDB Entry DOI: 10.7270/Q2610Z46
					More data for this Ligand-Target Pair