BDBM192940 US9193697, A7.29

SMILES: CN(C)CCOC(=O)N1CCC(CC1)c1nc(c(Sc2ccc(Cl)cn2)o1)-c1ccc(cc1)S(C)=O

InChI Key: InChIKey=KKWXUSLAHLIKGZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192940   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM192940 (US9193697, A7.29) Show SMILES CN(C)CCOC(=O)N1CCC(CC1)c1nc(c(Sc2ccc(Cl)cn2)o1)-c1ccc(cc1)S(C)=O Show InChI InChI=1S/C25H29ClN4O4S2/c1-29(2)14-15-33-25(31)30-12-10-18(11-13-30)23-28-22(17-4-7-20(8-5-17)36(3)32)24(34-23)35-21-9-6-19(26)16-27-21/h4-9,16,18H,10-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
MERCK SHARP & DOHME CORP. US Patent					Assay Description Enzyme activity was demonstrated in a radioenzymatic test based on measuring the product of hydrolysis (ethanolamine [3]H) of anandamide [ethanolam...				US Patent US9193697 (2015) BindingDB Entry DOI: 10.7270/Q2610Z46
					More data for this Ligand-Target Pair