BDBM192977 US9193697, B5.15

SMILES: Clc1ccc(Sc2oc(nc2C2=CCCNC2)C2CCOCC2)cc1

InChI Key: InChIKey=KOEGRWLCBDOWOK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM192977 (US9193697, B5.15) Show SMILES Clc1ccc(Sc2oc(nc2C2=CCCNC2)C2CCOCC2)cc1 |t:12| Show InChI InChI=1S/C19H21ClN2O2S/c20-15-3-5-16(6-4-15)25-19-17(14-2-1-9-21-12-14)22-18(24-19)13-7-10-23-11-8-13/h2-6,13,21H,1,7-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
MERCK SHARP & DOHME CORP. US Patent					Assay Description Enzyme activity was demonstrated in a radioenzymatic test based on measuring the product of hydrolysis (ethanolamine [3]H) of anandamide [ethanolam...				US Patent US9193697 (2015) BindingDB Entry DOI: 10.7270/Q2610Z46
					More data for this Ligand-Target Pair