BDBM193035 US9193726, 23

SMILES: Cc1cn(cn1)-c1ccc2C(=O)N(CC3CCCC(C3)c3ccc(Cl)cc3)CCn2c1=O

InChI Key: InChIKey=WMGXCCCFAWKKGK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193035   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM193035 (US9193726, 23) Show SMILES Cc1cn(cn1)-c1ccc2C(=O)N(CC3CCCC(C3)c3ccc(Cl)cc3)CCn2c1=O Show InChI InChI=1S/C25H27ClN4O2/c1-17-14-29(16-27-17)22-9-10-23-24(31)28(11-12-30(23)25(22)32)15-18-3-2-4-20(13-18)19-5-7-21(26)8-6-19/h5-10,14,16,18,20H,2-4,11-13,15H2,1H3	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description The ability of compounds to modulate production of amyloid beta protein Abeta(1-42) was determined using human WT-APP overexpressing CHO cells. Cel...				US Patent US9193726 (2015) BindingDB Entry DOI: 10.7270/Q22B8WT7
					More data for this Ligand-Target Pair