BDBM193145 US9193736, 61

SMILES: OC(=O)c1ccc(s1)-c1c(CCc2ccc3ccccc3n2)nc2c(ccnn12)N1CCOCC1

InChI Key: InChIKey=KKBVOEGVABXPPK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 193145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human))	BDBM193145 (US9193736, 61) Show SMILES OC(=O)c1ccc(s1)-c1c(CCc2ccc3ccccc3n2)nc2c(ccnn12)N1CCOCC1 Show InChI InChI=1S/C26H23N5O3S/c32-26(33)23-10-9-22(35-23)24-20(8-7-18-6-5-17-3-1-2-4-19(17)28-18)29-25-21(11-12-27-31(24)25)30-13-15-34-16-14-30/h1-6,9-12H,7-8,13-16H2,(H,32,33)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica, NV US Patent					Assay Description Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...				US Patent US9193736 (2015) BindingDB Entry DOI: 10.7270/Q2XK8DCS
					More data for this Ligand-Target Pair
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM193145 (US9193736, 61) Show SMILES OC(=O)c1ccc(s1)-c1c(CCc2ccc3ccccc3n2)nc2c(ccnn12)N1CCOCC1 Show InChI InChI=1S/C26H23N5O3S/c32-26(33)23-10-9-22(35-23)24-20(8-7-18-6-5-17-3-1-2-4-19(17)28-18)29-25-21(11-12-27-31(24)25)30-13-15-34-16-14-30/h1-6,9-12H,7-8,13-16H2,(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.8	n/a
Janssen Pharmaceutica, NV US Patent					Assay Description Rat recombinant PDE10a (rPDE10a) was expressed in Sf9 cells using a recombinant rPDE10a baculovirus construct. Cells were harvested after 48 h of inf...				US Patent US9193736 (2015) BindingDB Entry DOI: 10.7270/Q2XK8DCS
					More data for this Ligand-Target Pair