BDBM19330 (2R)-N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]piperidine-2-carboxamide::Trisubstituted 1,2,4-Triazole, 38
SMILES: CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCCN2)cc1
InChI Key: InChIKey=QDDCAAMEEYUGOX-ROJLCIKYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Ghrelin receptor (Homo sapiens (Human)) | BDBM19330 ((2R)-N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-phe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS | Assay Description Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co... | J Med Chem 50: 5790-5806 (2007) Article DOI: 10.1021/jm0704550 BindingDB Entry DOI: 10.7270/Q2HD7SZ4 | |||||||||||
More data for this Ligand-Target Pair |