BDBM193351 US9199927, 62

SMILES: NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CCC(=O)N(CC(O)=O)Cc2ccccc2)c(Cl)c1

InChI Key: InChIKey=LZIGPVRBBXQNMS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 193351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trypsinogen 16 (Mus musculus (Mouse))	BDBM193351 (US9199927, 62) Show SMILES NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CCC(=O)N(CC(O)=O)Cc2ccccc2)c(Cl)c1 Show InChI InChI=1S/C26H25ClN4O5/c27-22-14-21(36-25(35)19-6-10-20(11-7-19)30-26(28)29)12-8-18(22)9-13-23(32)31(16-24(33)34)15-17-4-2-1-3-5-17/h1-8,10-12,14H,9,13,15-16H2,(H,33,34)(H4,28,29,30)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.170	n/a	n/a	n/a	n/a	8.0	25
Astellas Pharma Inc. US Patent					Assay Description The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...				US Patent US9199927 (2015) BindingDB Entry DOI: 10.7270/Q2P26WXN
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM193351 (US9199927, 62) Show SMILES NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CCC(=O)N(CC(O)=O)Cc2ccccc2)c(Cl)c1 Show InChI InChI=1S/C26H25ClN4O5/c27-22-14-21(36-25(35)19-6-10-20(11-7-19)30-26(28)29)12-8-18(22)9-13-23(32)31(16-24(33)34)15-17-4-2-1-3-5-17/h1-8,10-12,14H,9,13,15-16H2,(H,33,34)(H4,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.290	n/a	n/a	n/a	n/a	8.0	25
Astellas Pharma Inc. US Patent					Assay Description The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...				US Patent US9199927 (2015) BindingDB Entry DOI: 10.7270/Q2P26WXN
					More data for this Ligand-Target Pair