null

SMILES: NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CCN(CC(O)=O)C(=O)Cc2cccc(c2)C(O)=O)c(Cl)c1

InChI Key: InChIKey=CJOJWDDLQJHGLU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 193355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trypsinogen 16 (Mus musculus (Mouse))	BDBM193355 (US9199927, 66) Show SMILES NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CCN(CC(O)=O)C(=O)Cc2cccc(c2)C(O)=O)c(Cl)c1 Show InChI InChI=1S/C27H25ClN4O7/c28-22-14-21(39-26(38)18-4-7-20(8-5-18)31-27(29)30)9-6-17(22)10-11-32(15-24(34)35)23(33)13-16-2-1-3-19(12-16)25(36)37/h1-9,12,14H,10-11,13,15H2,(H,34,35)(H,36,37)(H4,29,30,31)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.450	n/a	n/a	n/a	n/a	8.0	25
Astellas Pharma Inc. US Patent					Assay Description The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...				US Patent US9199927 (2015) BindingDB Entry DOI: 10.7270/Q2P26WXN
					More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM193355 (US9199927, 66) Show SMILES NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CCN(CC(O)=O)C(=O)Cc2cccc(c2)C(O)=O)c(Cl)c1 Show InChI InChI=1S/C27H25ClN4O7/c28-22-14-21(39-26(38)18-4-7-20(8-5-18)31-27(29)30)9-6-17(22)10-11-32(15-24(34)35)23(33)13-16-2-1-3-19(12-16)25(36)37/h1-9,12,14H,10-11,13,15H2,(H,34,35)(H,36,37)(H4,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.350	n/a	n/a	n/a	n/a	8.0	25
Astellas Pharma Inc. US Patent					Assay Description The compound was dissolved in dimethyl sulfoxide (DMSO), and diluted to an arbitrary concentration (A). A was 100-fold diluted with a buffer (0.1 M T...				US Patent US9199927 (2015) BindingDB Entry DOI: 10.7270/Q2P26WXN
					More data for this Ligand-Target Pair