BDBM19336 N-[(1R)-2-(1H-indol-3-yl)-1-[4-phenyl-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl]ethyl]piperidine-4-carboxamide::Trisubstituted 1,2,4-Triazole, 44

SMILES: O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2ccccc2)n1-c1ccccc1)C1CCNCC1

InChI Key: InChIKey=HTCGKPAHGQFWCF-GDLZYMKVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM19336 (N-[(1R)-2-(1H-indol-3-yl)-1-[4-phenyl-5-(2-phenyle...) Show SMILES O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2ccccc2)n1-c1ccccc1)C1CCNCC1 |r| Show InChI InChI=1S/C32H34N6O/c39-32(24-17-19-33-20-18-24)35-29(21-25-22-34-28-14-8-7-13-27(25)28)31-37-36-30(16-15-23-9-3-1-4-10-23)38(31)26-11-5-2-6-12-26/h1-14,22,24,29,33-34H,15-21H2,(H,35,39)/t29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	468	n/a	n/a	n/a	n/a	n/a	n/a
CNRS					Assay Description Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...				J Med Chem 50: 5790-5806 (2007) Article DOI: 10.1021/jm0704550 BindingDB Entry DOI: 10.7270/Q2HD7SZ4
					More data for this Ligand-Target Pair