BDBM193740 1-(3-(2-(1,3-Dioxo-1,3-diphenylpropan-2-ylidene)hydrazinyl)phenyl)-5-phenyl-N3,N4-bis(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-1Hpyrazole-3,4-dicarboxamide (8)

SMILES: [#7]S(=O)(=O)c1nnc(-[#7]-[#6](=O)-c2nn(c(c2-[#6](=O)-[#7]-c2nnc(s2)S([#7])(=O)=O)-c2ccccc2)-c2cccc(-[#7]\[#7]=[#6](/[#6](=O)-c3ccccc3)-[#6](=O)-c3ccccc3)c2)s1

InChI Key: InChIKey=MLQNOCCJNGDKOU-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 193740   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM193740 (1-(3-(2-(1,3-Dioxo-1,3-diphenylpropan-2-ylidene)hy...) Show SMILES [#7]S(=O)(=O)c1nnc(-[#7]-[#6](=O)-c2nn(c(c2-[#6](=O)-[#7]-c2nnc(s2)S([#7])(=O)=O)-c2ccccc2)-c2cccc(-[#7]\[#7]=[#6](/[#6](=O)-c3ccccc3)-[#6](=O)-c3ccccc3)c2)s1 Show InChI InChI=1S/C36H26N12O8S4/c37-59(53,54)35-45-43-33(57-35)39-31(51)25-26(32(52)40-34-44-46-36(58-34)60(38,55)56)47-48(28(25)20-11-4-1-5-12-20)24-18-10-17-23(19-24)41-42-27(29(49)21-13-6-2-7-14-21)30(50)22-15-8-3-9-16-22/h1-19,41H,(H2,37,53,54)(H2,38,55,56)(H,39,43,51)(H,40,44,52)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	878	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dumlupinar University					Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...				Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM193740 (1-(3-(2-(1,3-Dioxo-1,3-diphenylpropan-2-ylidene)hy...) Show SMILES [#7]S(=O)(=O)c1nnc(-[#7]-[#6](=O)-c2nn(c(c2-[#6](=O)-[#7]-c2nnc(s2)S([#7])(=O)=O)-c2ccccc2)-c2cccc(-[#7]\[#7]=[#6](/[#6](=O)-c3ccccc3)-[#6](=O)-c3ccccc3)c2)s1 Show InChI InChI=1S/C36H26N12O8S4/c37-59(53,54)35-45-43-33(57-35)39-31(51)25-26(32(52)40-34-44-46-36(58-34)60(38,55)56)47-48(28(25)20-11-4-1-5-12-20)24-18-10-17-23(19-24)41-42-27(29(49)21-13-6-2-7-14-21)30(50)22-15-8-3-9-16-22/h1-19,41H,(H2,37,53,54)(H2,38,55,56)(H,39,43,51)(H,40,44,52)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dumlupinar University					Assay Description CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...				Bioorg Chem 68: 64-71 (2016) Article DOI: 10.1016/j.bioorg.2016.07.006 BindingDB Entry DOI: 10.7270/Q2N29VQC
					More data for this Ligand-Target Pair