BDBM193881 2-{[2-(2,4-Dichlorobenzyl)-6-nitro-1H-benzimidazol-1-yl]acetyl}-N-phenyl hydrazinecarbothioamide (6b)

SMILES: [O-][N+](=O)c1ccc2nc(Cc3ccc(Cl)cc3Cl)n(CC(=O)NNC(=S)Nc3ccccc3)c2c1

InChI Key: InChIKey=NBJIVDAWKVFGKQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193881   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
alpha-Glucosidase (α-glucosidase) (Saccharomyces cerevisiae (Yeast))	BDBM193881 (2-{[2-(2,4-Dichlorobenzyl)-6-nitro-1H-benzimidazol...) Show SMILES [O-][N+](=O)c1ccc2nc(Cc3ccc(Cl)cc3Cl)n(CC(=O)NNC(=S)Nc3ccccc3)c2c1 Show InChI InChI=1S/C23H18Cl2N6O3S/c24-15-7-6-14(18(25)11-15)10-21-27-19-9-8-17(31(33)34)12-20(19)30(21)13-22(32)28-29-23(35)26-16-4-2-1-3-5-16/h1-9,11-12H,10,13H2,(H,28,32)(H2,26,29,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30E+4	n/a	n/a	n/a	n/a	6.8	n/a
Recep Tayyip Erdogan University					Assay Description α-Glucosidase inhibition assay was performed spectrophotometrically. α-Glucosidase from Saccharomyces cerevisiae (Sigma-Aldrich) was dissol...				Bioorg Chem 68: 226-35 (2016) Article DOI: 10.1016/j.bioorg.2016.08.011 BindingDB Entry DOI: 10.7270/Q20C4TKG
					More data for this Ligand-Target Pair