BDBM193903 US9199976, 16

SMILES: NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(nc1)-c1ccc(Cl)s1

InChI Key: InChIKey=PUQCZOGBUKRXKB-HNNXBMFYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193903   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D Synthase (Homo sapiens (Human))	BDBM193903 (US9199976, 16) Show SMILES NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(nc1)-c1ccc(Cl)s1 |r| Show InChI InChI=1S/C19H16ClN3O2S/c20-17-9-8-16(26-17)14-7-6-13(11-22-14)19(25)23-15(18(21)24)10-12-4-2-1-3-5-12/h1-9,11,15H,10H2,(H2,21,24)(H,23,25)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	8.0	n/a
The University of Queensland US Patent					Assay Description The H-PGDS catalyzed conjugation of GSH and 1-chloro-2,4-dinitrobenzene (CDNB) was used as the biochemical assay for enzyme inhibition. Reactions wer...				US Patent US9199976 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K9Z
					More data for this Ligand-Target Pair