BDBM19425 N-[2-amino-5-(thiophen-2-yl)phenyl]quinoxaline-6-carboxamide::benzamide-type inhibitor, 21

SMILES: Nc1ccc(cc1NC(=O)c1ccc2nccnc2c1)-c1cccs1

InChI Key: InChIKey=IHJROTPCROQIGM-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 19425   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19425 (N-[2-amino-5-(thiophen-2-yl)phenyl]quinoxaline-6-c...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc2nccnc2c1)-c1cccs1 Show InChI InChI=1S/C19H14N4OS/c20-14-5-3-12(18-2-1-9-25-18)10-16(14)23-19(24)13-4-6-15-17(11-13)22-8-7-21-15/h1-11H,20H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc					Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...				J Med Chem 50: 5543-6 (2007) Article DOI: 10.1021/jm701079h BindingDB Entry DOI: 10.7270/Q2445JS2
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM19425 (N-[2-amino-5-(thiophen-2-yl)phenyl]quinoxaline-6-c...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc2nccnc2c1)-c1cccs1 Show InChI InChI=1S/C19H14N4OS/c20-14-5-3-12(18-2-1-9-25-18)10-16(14)23-19(24)13-4-6-15-17(11-13)22-8-7-21-15/h1-11H,20H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc					Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...				J Med Chem 50: 5543-6 (2007) Article DOI: 10.1021/jm701079h BindingDB Entry DOI: 10.7270/Q2445JS2
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM19425 (N-[2-amino-5-(thiophen-2-yl)phenyl]quinoxaline-6-c...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc2nccnc2c1)-c1cccs1 Show InChI InChI=1S/C19H14N4OS/c20-14-5-3-12(18-2-1-9-25-18)10-16(14)23-19(24)13-4-6-15-17(11-13)22-8-7-21-15/h1-11H,20H2,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc					Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...				J Med Chem 50: 5543-6 (2007) Article DOI: 10.1021/jm701079h BindingDB Entry DOI: 10.7270/Q2445JS2
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM19425 (N-[2-amino-5-(thiophen-2-yl)phenyl]quinoxaline-6-c...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc2nccnc2c1)-c1cccs1 Show InChI InChI=1S/C19H14N4OS/c20-14-5-3-12(18-2-1-9-25-18)10-16(14)23-19(24)13-4-6-15-17(11-13)22-8-7-21-15/h1-11H,20H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc					Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...				J Med Chem 50: 5543-6 (2007) Article DOI: 10.1021/jm701079h BindingDB Entry DOI: 10.7270/Q2445JS2
					More data for this Ligand-Target Pair