BDBM194512 US9205085, MSX- 134

SMILES: C(Nc1ccccn1)c1cccc(CNc2ccccn2)c1

InChI Key: InChIKey=IFIICJIEYBMUID-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 194512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 4 (Rattus norvegicus (Rat))	BDBM194512 (US9205085, MSX- 134) Show SMILES C(Nc1ccccn1)c1cccc(CNc2ccccn2)c1 Show InChI InChI=1S/C18H18N4/c1-3-10-19-17(8-1)21-13-15-6-5-7-16(12-15)14-22-18-9-2-4-11-20-18/h1-12H,13-14H2,(H,19,21)(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Emory University US Patent					Assay Description A synthetic 14-mer peptide, TN14003, was previously reported to block both SDF-1/CXCR4 mediated invasion in vitro and metastasis in vivo with a high ...				US Patent US9205085 (2015) BindingDB Entry DOI: 10.7270/Q2FF3R5M
					More data for this Ligand-Target Pair