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BDBM194732 US9670211, 1-2

SMILES: CS(=O)(=O)[C@H]1C[C@@H](C1)n1c(CN2C(=O)C3(CC3)c3ccncc23)nc2cc(Cl)ccc12

InChI Key: InChIKey=YGVOGAAQKQGSND-SHTZXODSSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 194732   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Major surface glycoprotein G


(Human respiratory syncytial virus A (strain Long))		BDBM194732
PNG
(US9670211, 1-2 )
Show SMILES CS(=O)(=O)[C@H]1C[C@@H](C1)n1c(CN2C(=O)C3(CC3)c3ccncc23)nc2cc(Cl)ccc12 |r,wU:4.3,wD:6.8,(.31,6.89,;.31,5.35,;-1.23,5.35,;1.85,5.35,;.31,3.81,;1.08,2.48,;-.25,1.71,;-1.02,3.04,;-.65,.22,;.25,-1.03,;1.79,-1.03,;2.56,-2.36,;4.1,-2.36,;4.87,-1.03,;4.58,-3.83,;5.35,-5.16,;6.12,-3.83,;3.33,-4.73,;3.17,-6.26,;1.76,-6.89,;.52,-5.98,;.68,-4.45,;2.09,-3.83,;-.65,-2.27,;-2.12,-1.8,;-3.45,-2.57,;-4.78,-1.8,;-6.12,-2.57,;-4.78,-.26,;-3.45,.51,;-2.12,-.26,)|
Show InChI InChI=1S/C22H21ClN4O3S/c1-31(29,30)15-9-14(10-15)27-18-3-2-13(23)8-17(18)25-20(27)12-26-19-11-24-7-4-16(19)22(5-6-22)21(26)28/h2-4,7-8,11,14-15H,5-6,9-10,12H2,1H3/t14-,15-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/an/an/an/an/an/a



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...

US Patent US9670211 (2017)


BindingDB Entry DOI: 10.7270/Q2C827GQ
More data for this
Ligand-Target Pair