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BDBM194733 US9670211, 2-1

SMILES: Clc1ccc2n(C3CC4(C3)CS(=O)(=O)C4)c(CN3C(=O)C4(CC4)c4ccncc34)nc2c1

InChI Key: InChIKey=XFJISQXBHQFJNW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 194733   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Major surface glycoprotein G


(Human respiratory syncytial virus A (strain Long))		BDBM194733
PNG
(US9670211, 2-1 )
Show SMILES Clc1ccc2n(C3CC4(C3)CS(=O)(=O)C4)c(CN3C(=O)C4(CC4)c4ccncc34)nc2c1
Show InChI InChI=1S/C23H21ClN4O3S/c24-14-1-2-18-17(7-14)26-20(28(18)15-8-22(9-15)12-32(30,31)13-22)11-27-19-10-25-6-3-16(19)23(4-5-23)21(27)29/h1-3,6-7,10,15H,4-5,8-9,11-13H2
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/an/an/an/an/an/a



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...

US Patent US9670211 (2017)


BindingDB Entry DOI: 10.7270/Q2C827GQ
More data for this
Ligand-Target Pair