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SMILES: Clc1cnc2n(C3CCS(=O)(=O)C3)c(CN3C(=O)C4(CC4)c4ccncc34)nc2c1

InChI Key: InChIKey=SOWCHDHBORPEKQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 194745   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Major surface glycoprotein G


(Human respiratory syncytial virus A (strain Long))		BDBM194745
PNG
(US9670211, 2-13 )
Show SMILES Clc1cnc2n(C3CCS(=O)(=O)C3)c(CN3C(=O)C4(CC4)c4ccncc34)nc2c1
Show InChI InChI=1S/C20H18ClN5O3S/c21-12-7-15-18(23-8-12)26(13-2-6-30(28,29)11-13)17(24-15)10-25-16-9-22-5-1-14(16)20(3-4-20)19(25)27/h1,5,7-9,13H,2-4,6,10-11H2
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/an/an/an/an/an/a



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
To measure anti-RSV activity of compounds, 96-well plates are seeded with 6×103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...

US Patent US9670211 (2017)


BindingDB Entry DOI: 10.7270/Q2C827GQ
More data for this
Ligand-Target Pair