BDBM194833 US9206184, 14

SMILES: COCc1c(CN2CC[C@](C)(N)C2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1

InChI Key: InChIKey=WNUXYTTWUXBQMA-DEOSSOPVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 194833   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM194833 (US9206184, 14) Show SMILES COCc1c(CN2CC[C@](C)(N)C2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1 |r| Show InChI InChI=1S/C24H30N6O2S/c1-14-7-15-9-19(33-22(15)18(8-14)32-4)20-16(11-31-3)17(10-29-6-5-24(2,26)12-29)30-21(20)23(25)27-13-28-30/h7-9,13H,5-6,10-12,26H2,1-4H3,(H2,25,27,28)/t24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM194833 (US9206184, 14) Show SMILES COCc1c(CN2CC[C@](C)(N)C2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1 |r| Show InChI InChI=1S/C24H30N6O2S/c1-14-7-15-9-19(33-22(15)18(8-14)32-4)20-16(11-31-3)17(10-29-6-5-24(2,26)12-29)30-21(20)23(25)27-13-28-30/h7-9,13H,5-6,10-12,26H2,1-4H3,(H2,25,27,28)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair