BDBM194961 US9206198, 16

SMILES: CO[C@@H](CN1CCC2(CN(C(=O)C2)C2=C(C)C(=O)OC2)CC1)c1ccc2C(=O)OCc2c1C

InChI Key: InChIKey=RCOHUIRGWOSLCK-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 194961   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM194961 (US9206198, 16) Show SMILES CO[C@@H](CN1CCC2(CN(C(=O)C2)C2=C(C)C(=O)OC2)CC1)c1ccc2C(=O)OCc2c1C |r,c:14| Show InChI InChI=1S/C25H30N2O6/c1-15-17(4-5-18-19(15)12-32-24(18)30)21(31-3)11-26-8-6-25(7-9-26)10-22(28)27(14-25)20-13-33-23(29)16(20)2/h4-5,21H,6-14H2,1-3H3/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	37
Merck Sharp & Dohme Corp. US Patent					Assay Description The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D...				US Patent US9206198 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86FH
					More data for this Ligand-Target Pair