BDBM195022 US9206198, 6A

SMILES: C[C@@H]1CC2(CCN(C[C@H](O)c3ccc4C(=O)OCc4c3C)CC2)C(=O)N1C1=CC(=O)OC1

InChI Key: InChIKey=AIEOJVXEQZIAPD-VLIAUNLRSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 195022   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM195022 (US9206198, 6A) Show SMILES C[C@@H]1CC2(CCN(C[C@H](O)c3ccc4C(=O)OCc4c3C)CC2)C(=O)N1C1=CC(=O)OC1 |r,t:30| Show InChI InChI=1S/C24H28N2O6/c1-14-10-24(23(30)26(14)16-9-21(28)31-12-16)5-7-25(8-6-24)11-20(27)17-3-4-18-19(15(17)2)13-32-22(18)29/h3-4,9,14,20,27H,5-8,10-13H2,1-2H3/t14-,20+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	37
Merck Sharp & Dohme Corp. US Patent					Assay Description The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D...				US Patent US9206198 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86FH
					More data for this Ligand-Target Pair