BDBM195027 US9206198, 35

SMILES: CC1CN(C(=O)C11CCN(C[C@@H](O)c2ccc3C(=O)OCc3c2C)CC1)C1=C(C)C(=O)OC1

InChI Key: InChIKey=HEWPEKJZIFHLOI-OKKPIIHCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 195027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM195027 (US9206198, 35) Show SMILES CC1CN(C(=O)C11CCN(C[C@@H](O)c2ccc3C(=O)OCc3c2C)CC1)C1=C(C)C(=O)OC1 |r,c:30| Show InChI InChI=1S/C25H30N2O6/c1-14-10-27(20-13-33-22(29)16(20)3)24(31)25(14)6-8-26(9-7-25)11-21(28)17-4-5-18-19(15(17)2)12-32-23(18)30/h4-5,14,21,28H,6-13H2,1-3H3/t14?,21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	37
Merck Sharp & Dohme Corp. US Patent					Assay Description The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D...				US Patent US9206198 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86FH
					More data for this Ligand-Target Pair