null

SMILES: C[C@H](Nc1nc2CCN(Cc2c(=O)n1CC#C)C(=O)c1ccc(Cl)cc1)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=VFBIKSRJAYHXKT-INIZCTEOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 195614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolactin-releasing peptide receptor (Homo sapiens (Human))	BDBM195614 (US9206173, 2) Show SMILES C[C@H](Nc1nc2CCN(Cc2c(=O)n1CC#C)C(=O)c1ccc(Cl)cc1)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C26H22ClF3N4O2/c1-3-13-34-24(36)21-15-33(23(35)18-6-10-20(27)11-7-18)14-12-22(21)32-25(34)31-16(2)17-4-8-19(9-5-17)26(28,29)30/h1,4-11,16H,12-15H2,2H3,(H,31,32)/t16-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	29	-10.3	n/a	n/a	n/a	n/a	n/a	7.4	25
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Receptor-expressing HEK 293 cell membrane fraction was analyzed by modifying the methods of C. J. Langmead et al. (see Langmead C J, Szekeres P G; Ch...				US Patent US9206173 (2015) BindingDB Entry DOI: 10.7270/Q23X85FS
					More data for this Ligand-Target Pair
Prolactin-releasing peptide receptor (Homo sapiens (Human))	BDBM195614 (US9206173, 2) Show SMILES C[C@H](Nc1nc2CCN(Cc2c(=O)n1CC#C)C(=O)c1ccc(Cl)cc1)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C26H22ClF3N4O2/c1-3-13-34-24(36)21-15-33(23(35)18-6-10-20(27)11-7-18)14-12-22(21)32-25(34)31-16(2)17-4-8-19(9-5-17)26(28,29)30/h1,4-11,16H,12-15H2,2H3,(H,31,32)/t16-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	378	n/a	n/a	n/a	n/a	7.4	25
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description HEK293 cells expressing human GPR10 were maintained in Dulbecco's Modified Eagles' medium supplemented with 10% fetal bovine serum, 1% penici...				US Patent US9206173 (2015) BindingDB Entry DOI: 10.7270/Q23X85FS
					More data for this Ligand-Target Pair