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SMILES: COn1c(NC(C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)c1cc2cccnc2s1

InChI Key: InChIKey=LVWFGIIPYWSKIX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 195653   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prolactin-releasing peptide receptor


(Homo sapiens (Human))		BDBM195653
PNG
(US9206173, 2415)
Show SMILES COn1c(NC(C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)c1cc2cccnc2s1
Show InChI InChI=1S/C25H22F3N5O3S/c1-14(15-5-7-17(8-6-15)25(26,27)28)30-24-31-19-9-11-32(13-18(19)22(34)33(24)36-2)23(35)20-12-16-4-3-10-29-21(16)37-20/h3-8,10,12,14H,9,11,13H2,1-2H3,(H,30,31)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
 9 -11.0n/an/an/an/an/a7.425



OTSUKA PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Receptor-expressing HEK 293 cell membrane fraction was analyzed by modifying the methods of C. J. Langmead et al. (see Langmead C J, Szekeres P G; Ch...

US Patent US9206173 (2015)


BindingDB Entry DOI: 10.7270/Q23X85FS
More data for this
Ligand-Target Pair