BDBM19581 (2S)-2-{[5-(4-chlorophenyl)furan-2-yl]formamido}-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]ethyl}propanamide::arylaminoethyl amide, 19

SMILES: COc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)cc1

InChI Key: InChIKey=PWLIJBOOAOUCQG-VWLOTQADSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin S (Homo sapiens (Human))	BDBM19581 ((2S)-2-{[5-(4-chlorophenyl)furan-2-yl]formamido}-3...) Show SMILES COc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C29H34ClN3O4/c1-36-24-13-11-23(12-14-24)31-17-18-32-28(34)25(19-20-5-3-2-4-6-20)33-29(35)27-16-15-26(37-27)21-7-9-22(30)10-8-21/h7-16,20,25,31H,2-6,17-19H2,1H3,(H,32,34)(H,33,35)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GNF					Assay Description The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...				Bioorg Med Chem Lett 15: 4979-84 (2005) Article DOI: 10.1016/j.bmcl.2005.08.017 BindingDB Entry DOI: 10.7270/Q2ZG6QJ8
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM19581 ((2S)-2-{[5-(4-chlorophenyl)furan-2-yl]formamido}-3...) Show SMILES COc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C29H34ClN3O4/c1-36-24-13-11-23(12-14-24)31-17-18-32-28(34)25(19-20-5-3-2-4-6-20)33-29(35)27-16-15-26(37-27)21-7-9-22(30)10-8-21/h7-16,20,25,31H,2-6,17-19H2,1H3,(H,32,34)(H,33,35)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>6.44E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GNF					Assay Description The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...				Bioorg Med Chem Lett 15: 4979-84 (2005) Article DOI: 10.1016/j.bmcl.2005.08.017 BindingDB Entry DOI: 10.7270/Q2ZG6QJ8
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM19581 ((2S)-2-{[5-(4-chlorophenyl)furan-2-yl]formamido}-3...) Show SMILES COc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C29H34ClN3O4/c1-36-24-13-11-23(12-14-24)31-17-18-32-28(34)25(19-20-5-3-2-4-6-20)33-29(35)27-16-15-26(37-27)21-7-9-22(30)10-8-21/h7-16,20,25,31H,2-6,17-19H2,1H3,(H,32,34)(H,33,35)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GNF					Assay Description The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...				Bioorg Med Chem Lett 15: 4979-84 (2005) Article DOI: 10.1016/j.bmcl.2005.08.017 BindingDB Entry DOI: 10.7270/Q2ZG6QJ8
					More data for this Ligand-Target Pair