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SMILES: COC(=O)Cn1c(=O)cc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O

InChI Key: InChIKey=VXCLKDJVSMOYIR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196206   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2X purinoceptor 3


(Homo sapiens (Human))		BDBM196206
PNG
(US9212130, I-104)
Show SMILES COC(=O)Cn1c(=O)cc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C23H23ClFN3O5/c1-14(2)33-19-9-8-17(10-18(19)25)26-20-11-21(29)28(13-22(30)32-3)23(31)27(20)12-15-4-6-16(24)7-5-15/h4-11,14,26H,12-13H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 96n/an/an/an/a7.5n/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...

US Patent US9212130 (2015)


BindingDB Entry DOI: 10.7270/Q2BG2MS2
More data for this
Ligand-Target Pair