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SMILES: CC(C)Oc1ccc(Nc2cc(=O)n(CCCC(O)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl

InChI Key: InChIKey=QIJQSCRAGIBWKA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196208   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2X purinoceptor 3


(Homo sapiens (Human))		BDBM196208
PNG
(US9212130, I-106)
Show SMILES CC(C)Oc1ccc(Nc2cc(=O)n(CCCC(O)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl
Show InChI InChI=1S/C24H25Cl2N3O5/c1-15(2)34-20-10-9-18(12-19(20)26)27-21-13-22(30)28(11-3-4-23(31)32)24(33)29(21)14-16-5-7-17(25)8-6-16/h5-10,12-13,15,27H,3-4,11,14H2,1-2H3,(H,31,32)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 34n/an/an/an/a7.5n/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...

US Patent US9212130 (2015)


BindingDB Entry DOI: 10.7270/Q2BG2MS2
More data for this
Ligand-Target Pair