null

SMILES: CC(CC(O)=O)N1CCc2oc(nc2C1)-c1ccc(OCc2cccc(F)c2F)cc1

InChI Key: InChIKey=ISKOJBCBMGSCTH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 196211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM196211 (US9670220, 175) Show SMILES CC(CC(O)=O)N1CCc2oc(nc2C1)-c1ccc(OCc2cccc(F)c2F)cc1 Show InChI InChI=1S/C23H22F2N2O4/c1-14(11-21(28)29)27-10-9-20-19(12-27)26-23(31-20)15-5-7-17(8-6-15)30-13-16-3-2-4-18(24)22(16)25/h2-8,14H,9-13H2,1H3,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM196211 (US9670220, 175) Show SMILES CC(CC(O)=O)N1CCc2oc(nc2C1)-c1ccc(OCc2cccc(F)c2F)cc1 Show InChI InChI=1S/C23H22F2N2O4/c1-14(11-21(28)29)27-10-9-20-19(12-27)26-23(31-20)15-5-7-17(8-6-15)30-13-16-3-2-4-18(24)22(16)25/h2-8,14H,9-13H2,1H3,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM196211 (US9670220, 175) Show SMILES CC(CC(O)=O)N1CCc2oc(nc2C1)-c1ccc(OCc2cccc(F)c2F)cc1 Show InChI InChI=1S/C23H22F2N2O4/c1-14(11-21(28)29)27-10-9-20-19(12-27)26-23(31-20)15-5-7-17(8-6-15)30-13-16-3-2-4-18(24)22(16)25/h2-8,14H,9-13H2,1H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>3.20E+3	n/a	n/a	n/a	25
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair