null

SMILES: OC(=O)[C@H]1CC(C1)N1CCc2oc(nc2C1)-c1ccc(OCc2ccc(F)c(F)c2)cc1

InChI Key: InChIKey=XDNHODKJEVRGMW-XPIKVJKASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 196263   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM196263 (US9670220, 277) Show SMILES OC(=O)[C@H]1CC(C1)N1CCc2oc(nc2C1)-c1ccc(OCc2ccc(F)c(F)c2)cc1 |r,wU:3.2,(10.37,-1.61,;9.12,-2.52,;7.72,-1.89,;9.28,-4.05,;8.81,-5.51,;7.28,-5.35,;7.75,-3.89,;5.94,-6.12,;5.94,-7.66,;4.61,-8.43,;3.28,-7.66,;1.81,-8.14,;.91,-6.89,;1.81,-5.65,;3.28,-6.12,;4.61,-5.35,;-.64,-6.89,;-1.41,-8.23,;-2.94,-8.23,;-3.72,-6.89,;-5.26,-6.89,;-6.03,-5.56,;-7.57,-5.56,;-8.34,-6.89,;-9.88,-6.89,;-10.65,-5.56,;-12.19,-5.56,;-9.88,-4.22,;-10.65,-2.89,;-8.34,-4.23,;-2.94,-5.56,;-1.41,-5.56,)| Show InChI InChI=1S/C24H22F2N2O4/c25-19-6-1-14(9-20(19)26)13-31-18-4-2-15(3-5-18)23-27-21-12-28(8-7-22(21)32-23)17-10-16(11-17)24(29)30/h1-6,9,16-17H,7-8,10-13H2,(H,29,30)/t16-,17?	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM196263 (US9670220, 277) Show SMILES OC(=O)[C@H]1CC(C1)N1CCc2oc(nc2C1)-c1ccc(OCc2ccc(F)c(F)c2)cc1 |r,wU:3.2,(10.37,-1.61,;9.12,-2.52,;7.72,-1.89,;9.28,-4.05,;8.81,-5.51,;7.28,-5.35,;7.75,-3.89,;5.94,-6.12,;5.94,-7.66,;4.61,-8.43,;3.28,-7.66,;1.81,-8.14,;.91,-6.89,;1.81,-5.65,;3.28,-6.12,;4.61,-5.35,;-.64,-6.89,;-1.41,-8.23,;-2.94,-8.23,;-3.72,-6.89,;-5.26,-6.89,;-6.03,-5.56,;-7.57,-5.56,;-8.34,-6.89,;-9.88,-6.89,;-10.65,-5.56,;-12.19,-5.56,;-9.88,-4.22,;-10.65,-2.89,;-8.34,-4.23,;-2.94,-5.56,;-1.41,-5.56,)| Show InChI InChI=1S/C24H22F2N2O4/c25-19-6-1-14(9-20(19)26)13-31-18-4-2-15(3-5-18)23-27-21-12-28(8-7-22(21)32-23)17-10-16(11-17)24(29)30/h1-6,9,16-17H,7-8,10-13H2,(H,29,30)/t16-,17?	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM196263 (US9670220, 277) Show SMILES OC(=O)[C@H]1CC(C1)N1CCc2oc(nc2C1)-c1ccc(OCc2ccc(F)c(F)c2)cc1 |r,wU:3.2,(10.37,-1.61,;9.12,-2.52,;7.72,-1.89,;9.28,-4.05,;8.81,-5.51,;7.28,-5.35,;7.75,-3.89,;5.94,-6.12,;5.94,-7.66,;4.61,-8.43,;3.28,-7.66,;1.81,-8.14,;.91,-6.89,;1.81,-5.65,;3.28,-6.12,;4.61,-5.35,;-.64,-6.89,;-1.41,-8.23,;-2.94,-8.23,;-3.72,-6.89,;-5.26,-6.89,;-6.03,-5.56,;-7.57,-5.56,;-8.34,-6.89,;-9.88,-6.89,;-10.65,-5.56,;-12.19,-5.56,;-9.88,-4.22,;-10.65,-2.89,;-8.34,-4.23,;-2.94,-5.56,;-1.41,-5.56,)| Show InChI InChI=1S/C24H22F2N2O4/c25-19-6-1-14(9-20(19)26)13-31-18-4-2-15(3-5-18)23-27-21-12-28(8-7-22(21)32-23)17-10-16(11-17)24(29)30/h1-6,9,16-17H,7-8,10-13H2,(H,29,30)/t16-,17?	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-human-S1P1-Acqorin assay was bought from Euroscreen Fast, Brussels (Euroscreen, Technical dossier, Human S1P1 (Edg1) receptor, DNA clone a...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair