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SMILES: CC(C)Oc1ccc(Nc2nc(=O)c3cc(ccc3n2Cc2ccc(Cl)cc2)C(F)(F)F)cc1Cl

InChI Key: InChIKey=HMGUDWVQXPKOKJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196308   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2X purinoceptor 3


(Homo sapiens (Human))		BDBM196308
PNG
(US9212130, I-227)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)c3cc(ccc3n2Cc2ccc(Cl)cc2)C(F)(F)F)cc1Cl
Show InChI InChI=1S/C25H20Cl2F3N3O2/c1-14(2)35-22-10-8-18(12-20(22)27)31-24-32-23(34)19-11-16(25(28,29)30)5-9-21(19)33(24)13-15-3-6-17(26)7-4-15/h3-12,14H,13H2,1-2H3,(H,31,32,34)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 974n/an/an/an/a7.5n/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...

US Patent US9212130 (2015)


BindingDB Entry DOI: 10.7270/Q2BG2MS2
More data for this
Ligand-Target Pair