null

SMILES: OC[C@@H](O)Cc1cn(-c2ccc(cc2)S(=O)(=O)Nc2ccc(F)cc2)c2ccccc12

InChI Key: InChIKey=OCGFKSGAKUPPQD-FQEVSTJZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 196470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM196470 (US10202344, Compound 92 | US9212139, 92) Show SMILES OC[C@@H](O)Cc1cn(-c2ccc(cc2)S(=O)(=O)Nc2ccc(F)cc2)c2ccccc12 Show InChI InChI=1S/C23H21FN2O4S/c24-17-5-7-18(8-6-17)25-31(29,30)21-11-9-19(10-12-21)26-14-16(13-20(28)15-27)22-3-1-2-4-23(22)26/h1-12,14,20,25,27-28H,13,15H2/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...				US Patent US10202344 (2019) BindingDB Entry DOI: 10.7270/Q2X350KJ
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM196470 (US10202344, Compound 92 | US9212139, 92) Show SMILES OC[C@@H](O)Cc1cn(-c2ccc(cc2)S(=O)(=O)Nc2ccc(F)cc2)c2ccccc12 Show InChI InChI=1S/C23H21FN2O4S/c24-17-5-7-18(8-6-17)25-31(29,30)21-11-9-19(10-12-21)26-14-16(13-20(28)15-27)22-3-1-2-4-23(22)26/h1-12,14,20,25,27-28H,13,15H2/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a	7.3	n/a
Purdue Pharma, L.P. US Patent					Assay Description Assay Buffer: The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL...				US Patent US9212139 (2015) BindingDB Entry DOI: 10.7270/Q26Q1W19
					More data for this Ligand-Target Pair