null
SMILES: Oc1n[nH]c(COc2ccc(F)cc2)cc1=O
InChI Key: InChIKey=DFARBTKATGLYKL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM196673 (US10202399, Example 231 | US9212147, 231) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di... | US Patent US9212147 (2015) BindingDB Entry DOI: 10.7270/Q29G5KKS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM196673 (US10202399, Example 231 | US9212147, 231) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di... | US Patent US10202399 (2019) BindingDB Entry DOI: 10.7270/Q2542QQD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM196673 (US10202399, Example 231 | US9212147, 231) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Takeda Pharmaceutical Company Limited US Patent | Assay Description This test was performed by partially modifying the method of Philip et. al. (J. Biomol. Screen. Vol. 11, pp 481-487, 2006). HEK293 cells that stably ... | US Patent US9212147 (2015) BindingDB Entry DOI: 10.7270/Q29G5KKS | |||||||||||
More data for this Ligand-Target Pair |