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SMILES: CN1CCCCC(c2ccc(cn2)C#Cc2ccccc2)C1=O

InChI Key: InChIKey=IUDGZOINZXJCGK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196697   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Isoform 1 of Metabotropic glutamate receptor 5 (5a)


(Homo sapiens (Human))		BDBM196697
PNG
(US9212171, 22)
Show SMILES CN1CCCCC(c2ccc(cn2)C#Cc2ccccc2)C1=O
Show InChI InChI=1S/C20H20N2O/c1-22-14-6-5-9-18(20(22)23)19-13-12-17(15-21-19)11-10-16-7-3-2-4-8-16/h2-4,7-8,12-13,15,18H,5-6,9,14H2,1H3
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 59n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...

US Patent US9212171 (2015)


BindingDB Entry DOI: 10.7270/Q25Q4TWH
More data for this
Ligand-Target Pair