BDBM196755 US9212173, 33

SMILES: CNc1nc(Nc2cnn(CCc3ccn(C)n3)c2C)ncc1C(F)(F)F

InChI Key: InChIKey=MEVDKBXULFFYOF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196755   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM196755 (US9212173, 33) Show SMILES CNc1nc(Nc2cnn(CCc3ccn(C)n3)c2C)ncc1C(F)(F)F Show InChI InChI=1S/C16H19F3N8/c1-10-13(9-22-27(10)7-5-11-4-6-26(3)25-11)23-15-21-8-12(16(17,18)19)14(20-2)24-15/h4,6,8-9H,5,7H2,1-3H3,(H2,20,21,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 3...				US Patent US9212173 (2015) BindingDB Entry DOI: 10.7270/Q2222SKT
					More data for this Ligand-Target Pair