BDBM196777 US9212178, 29::US9212178, 6

SMILES: CCn1cc(C(=O)C2CC2)c2cc(Nc3nccc(n3)-n3cc(CN4C[C@H](O)CO4)c(C)n3)ccc12

InChI Key: InChIKey=PWEKRGOZHHLNMO-FQEVSTJZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 196777   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM196777 (US9212178, 29 | US9212178, 6) Show SMILES CCn1cc(C(=O)C2CC2)c2cc(Nc3nccc(n3)-n3cc(CN4C[C@H](O)CO4)c(C)n3)ccc12 |r| Show InChI InChI=1S/C26H29N7O3/c1-3-31-14-22(25(35)17-4-5-17)21-10-19(6-7-23(21)31)28-26-27-9-8-24(29-26)33-12-18(16(2)30-33)11-32-13-20(34)15-36-32/h6-10,12,14,17,20,34H,3-5,11,13,15H2,1-2H3,(H,27,28,29)/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	69.5	n/a	n/a	n/a	n/a	n/a	25
Genosco; Oscotec, Inc. US Patent					Assay Description Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...				US Patent US9212178 (2015) BindingDB Entry DOI: 10.7270/Q2X9294C
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM196777 (US9212178, 29 | US9212178, 6) Show SMILES CCn1cc(C(=O)C2CC2)c2cc(Nc3nccc(n3)-n3cc(CN4C[C@H](O)CO4)c(C)n3)ccc12 |r| Show InChI InChI=1S/C26H29N7O3/c1-3-31-14-22(25(35)17-4-5-17)21-10-19(6-7-23(21)31)28-26-27-9-8-24(29-26)33-12-18(16(2)30-33)11-32-13-20(34)15-36-32/h6-10,12,14,17,20,34H,3-5,11,13,15H2,1-2H3,(H,27,28,29)/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.69	n/a	n/a	n/a	n/a	n/a	25
Genosco; Oscotec, Inc. US Patent					Assay Description Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...				US Patent US9212178 (2015) BindingDB Entry DOI: 10.7270/Q2X9294C
					More data for this Ligand-Target Pair