BDBM196786 US9212178, 15

SMILES: Cc1nn(cc1CN1C[C@H](O)CO1)-c1ccnc(Nc2ccc3n(CC(F)(F)F)cc(C(=O)C4CC4)c3c2)n1

InChI Key: InChIKey=LVECTQJBPIVAIR-IBGZPJMESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM196786 (US9212178, 15) Show SMILES Cc1nn(cc1CN1C[C@H](O)CO1)-c1ccnc(Nc2ccc3n(CC(F)(F)F)cc(C(=O)C4CC4)c3c2)n1 |r| Show InChI InChI=1S/C26H26F3N7O3/c1-15-17(9-35-11-19(37)13-39-35)10-36(33-15)23-6-7-30-25(32-23)31-18-4-5-22-20(8-18)21(24(38)16-2-3-16)12-34(22)14-26(27,28)29/h4-8,10,12,16,19,37H,2-3,9,11,13-14H2,1H3,(H,30,31,32)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.98	n/a	n/a	n/a	n/a	n/a	25
Genosco; Oscotec, Inc. US Patent					Assay Description Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...				US Patent US9212178 (2015) BindingDB Entry DOI: 10.7270/Q2X9294C
					More data for this Ligand-Target Pair