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SMILES: O[C@@H]1CON(Cc2cnn(c2)-c2ccnc(Nc3ccc4n(CC(F)(F)F)cc(C(=O)C5CC5)c4c3)n2)C1

InChI Key: InChIKey=YBDFABRBIIRYCZ-SFHVURJKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196805   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM196805
PNG
(US9212178, 34)
Show SMILES O[C@@H]1CON(Cc2cnn(c2)-c2ccnc(Nc3ccc4n(CC(F)(F)F)cc(C(=O)C5CC5)c4c3)n2)C1 |r|
Show InChI InChI=1S/C25H24F3N7O3/c26-25(27,28)14-33-12-20(23(37)16-1-2-16)19-7-17(3-4-21(19)33)31-24-29-6-5-22(32-24)35-10-15(8-30-35)9-34-11-18(36)13-38-34/h3-8,10,12,16,18,36H,1-2,9,11,13-14H2,(H,29,31,32)/t18-/m0/s1
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MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 5.80n/an/an/an/an/a25



Genosco; Oscotec, Inc.

US Patent


Assay Description
Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...

US Patent US9212178 (2015)


BindingDB Entry DOI: 10.7270/Q2X9294C
More data for this
Ligand-Target Pair