BDBM196815 US9212186, 8

SMILES: CCNc1nc(Nc2cnn3CCN(C)[C@H](C)c23)ncc1C(F)(F)F

InChI Key: InChIKey=HPGKXVFNOILWCK-SECBINFHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196815   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM196815 (US9212186, 8) Show SMILES CCNc1nc(Nc2cnn3CCN(C)[C@H](C)c23)ncc1C(F)(F)F |r| Show InChI InChI=1S/C15H20F3N7/c1-4-19-13-10(15(16,17)18)7-20-14(23-13)22-11-8-21-25-6-5-24(3)9(2)12(11)25/h7-9H,4-6H2,1-3H3,(H2,19,20,22,23)/t9-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	144	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 3...				US Patent US9212186 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SPX
					More data for this Ligand-Target Pair