BDBM196816 US9212186, 9

SMILES: C[C@@H]1N(C)CCn2ncc(Nc3ncc(c(NC4CC4)n3)C(F)(F)F)c12

InChI Key: InChIKey=CXWPUOGBKGFBIZ-VIFPVBQESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM196816 (US9212186, 9) Show SMILES C[C@@H]1N(C)CCn2ncc(Nc3ncc(c(NC4CC4)n3)C(F)(F)F)c12 |r| Show InChI InChI=1S/C16H20F3N7/c1-9-13-12(8-21-26(13)6-5-25(9)2)23-15-20-7-11(16(17,18)19)14(24-15)22-10-3-4-10/h7-10H,3-6H2,1-2H3,(H2,20,22,23,24)/t9-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 3...				US Patent US9212186 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SPX
					More data for this Ligand-Target Pair