BDBM196854 US9212192, 17
SMILES: Cc1cc(Nc2nc(Cc3c(Cl)cccc3Cl)n3cnnc3c2C(N)=O)ccc1N1CCNCC1
InChI Key: InChIKey=MXSVHPKONHQGSS-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM196854 (US9212192, 17) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <1 | <-12.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
AbbVie Inc. US Patent | Assay Description ALK kinase assays were conducted with the indicated final concentrations unless otherwise specified. In 384 well black plates (Axygen), 8 ul of compo... | US Patent US9212192 (2015) BindingDB Entry DOI: 10.7270/Q2D79971 | |||||||||||
More data for this Ligand-Target Pair |