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BDBM196927 US9212196, Derivative 23

SMILES: N[C@H](CCP(O)(=O)C(O)c1ccc(OCC(O)=O)c(c1)C(O)=O)C(O)=O

InChI Key: InChIKey=HLBMHNZCZUXUSO-OLSSVRIGNA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 196927   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4 (mGlu4)


(Rattus norvegicus (Rat))
BDBM196927
PNG
(US9212196, Derivative 23)
Show SMILES N[C@H](CCP(O)(=O)C(O)c1ccc(OCC(O)=O)c(c1)C(O)=O)C(O)=O
Show InChI InChI=1/C14H18NO10P/c15-9(13(20)21)3-4-26(23,24)14(22)7-1-2-10(25-6-11(16)17)8(5-7)12(18)19/h1-2,5,9,14,22H,3-4,6,15H2,(H,16,17)(H,18,19)(H,20,21)(H,23,24)/t9-,14?/s2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 4.00E+3n/an/an/an/a



UNIVERSITE PARIS DESCARTES; UNIVERSITE D'AUVERGNE

US Patent


Assay Description
Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 7 (mGlu7)


(Rattus norvegicus (Rat))
BDBM196927
PNG
(US9212196, Derivative 23)
Show SMILES N[C@H](CCP(O)(=O)C(O)c1ccc(OCC(O)=O)c(c1)C(O)=O)C(O)=O
Show InChI InChI=1/C14H18NO10P/c15-9(13(20)21)3-4-26(23,24)14(22)7-1-2-10(25-6-11(16)17)8(5-7)12(18)19/h1-2,5,9,14,22H,3-4,6,15H2,(H,16,17)(H,18,19)(H,20,21)(H,23,24)/t9-,14?/s2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 6.50E+4n/an/an/an/a



UNIVERSITE PARIS DESCARTES; UNIVERSITE D'AUVERGNE

US Patent


Assay Description
Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...


Citation and Details
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 8 (mGlu8)


(Rattus norvegicus (Rat))
BDBM196927
PNG
(US9212196, Derivative 23)
Show SMILES N[C@H](CCP(O)(=O)C(O)c1ccc(OCC(O)=O)c(c1)C(O)=O)C(O)=O
Show InChI InChI=1/C14H18NO10P/c15-9(13(20)21)3-4-26(23,24)14(22)7-1-2-10(25-6-11(16)17)8(5-7)12(18)19/h1-2,5,9,14,22H,3-4,6,15H2,(H,16,17)(H,18,19)(H,20,21)(H,23,24)/t9-,14?/s2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 7.40E+3n/an/an/an/a



UNIVERSITE PARIS DESCARTES; UNIVERSITE D'AUVERGNE

US Patent


Assay Description
Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...


Citation and Details
More data for this
Ligand-Target Pair