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SMILES: CCc1nn(Cc2ccc(cc2F)-c2nc3c(C)cccc3[nH]2)c(CC)c1CC(O)=O

InChI Key: InChIKey=KCLFBEBACIISRI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 197019   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM197019
PNG
(US9206164, 83)
Show SMILES CCc1nn(Cc2ccc(cc2F)-c2nc3c(C)cccc3[nH]2)c(CC)c1CC(O)=O
Show InChI InChI=1S/C24H25FN4O2/c1-4-19-17(12-22(30)31)21(5-2)29(28-19)13-16-10-9-15(11-18(16)25)24-26-20-8-6-7-14(3)23(20)27-24/h6-11H,4-5,12-13H2,1-3H3,(H,26,27)(H,30,31)
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US Patent
 1.30n/an/an/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...

US Patent US9206164 (2015)


BindingDB Entry DOI: 10.7270/Q2PR7TS9
More data for this
Ligand-Target Pair