null

SMILES: C[C@H](OP(O)(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)Cn1c2cc(=O)ccc2cc2c1[nH]c(=O)[nH]c2=O)C(=O)N[C@@H](CCC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O

InChI Key: InChIKey=XXFFZHQKSZLLIT-NALJQGANSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 197175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
F420-dependent glucose-6-phosphate dehydrogenase (Mycobacterium tuberculosis)	BDBM197175 (F420) Show SMILES C[C@H](OP(O)(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)Cn1c2cc(=O)ccc2cc2c1[nH]c(=O)[nH]c2=O)C(=O)N[C@@H](CCC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C29H36N5O18P/c1-12(25(42)31-17(28(46)47)4-6-21(38)30-16(27(44)45)5-7-22(39)40)52-53(49,50)51-11-20(37)23(41)19(36)10-34-18-9-14(35)3-2-13(18)8-15-24(34)32-29(48)33-26(15)43/h2-3,8-9,12,16-17,19-20,23,36-37,41H,4-7,10-11H2,1H3,(H,30,38)(H,31,42)(H,39,40)(H,44,45)(H,46,47)(H,49,50)(H2,32,33,43,48)/t12-,16-,17-,19-,20+,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6.60	n/a	n/a	n/a	7.0	n/a
The University of Texas at Arlington					Assay Description Fluorescence spectroscopy was used to determine the G6P and F420 dissociationconstants (Kd) for the FGD wild-type and mutant enzymes. A Spectrosil Qu...				Biochemistry 55: 5566-5577 (2016) Article DOI: 10.1021/acs.biochem.6b00638 BindingDB Entry DOI: 10.7270/Q2C8284N
					More data for this Ligand-Target Pair
F420-dependent glucose-6-phosphate dehydrogenase [W44F] (Mycobacterium tuberculosis)	BDBM197175 (F420) Show SMILES C[C@H](OP(O)(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)Cn1c2cc(=O)ccc2cc2c1[nH]c(=O)[nH]c2=O)C(=O)N[C@@H](CCC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C29H36N5O18P/c1-12(25(42)31-17(28(46)47)4-6-21(38)30-16(27(44)45)5-7-22(39)40)52-53(49,50)51-11-20(37)23(41)19(36)10-34-18-9-14(35)3-2-13(18)8-15-24(34)32-29(48)33-26(15)43/h2-3,8-9,12,16-17,19-20,23,36-37,41H,4-7,10-11H2,1H3,(H,30,38)(H,31,42)(H,39,40)(H,44,45)(H,46,47)(H,49,50)(H2,32,33,43,48)/t12-,16-,17-,19-,20+,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	22	n/a	n/a	n/a	7.0	n/a
The University of Texas at Arlington					Assay Description Fluorescence spectroscopy was used to determine the G6P and F420 dissociationconstants (Kd) for the FGD wild-type and mutant enzymes. A Spectrosil Qu...				Biochemistry 55: 5566-5577 (2016) Article DOI: 10.1021/acs.biochem.6b00638 BindingDB Entry DOI: 10.7270/Q2C8284N
					More data for this Ligand-Target Pair
F420-dependent glucose-6-phosphate dehydrogenase [H40A] (Mycobacterium tuberculosis)	BDBM197175 (F420) Show SMILES C[C@H](OP(O)(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)Cn1c2cc(=O)ccc2cc2c1[nH]c(=O)[nH]c2=O)C(=O)N[C@@H](CCC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C29H36N5O18P/c1-12(25(42)31-17(28(46)47)4-6-21(38)30-16(27(44)45)5-7-22(39)40)52-53(49,50)51-11-20(37)23(41)19(36)10-34-18-9-14(35)3-2-13(18)8-15-24(34)32-29(48)33-26(15)43/h2-3,8-9,12,16-17,19-20,23,36-37,41H,4-7,10-11H2,1H3,(H,30,38)(H,31,42)(H,39,40)(H,44,45)(H,46,47)(H,49,50)(H2,32,33,43,48)/t12-,16-,17-,19-,20+,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	150	n/a	n/a	n/a	7.0	n/a
The University of Texas at Arlington					Assay Description Fluorescence spectroscopy was used to determine the G6P and F420 dissociationconstants (Kd) for the FGD wild-type and mutant enzymes. A Spectrosil Qu...				Biochemistry 55: 5566-5577 (2016) Article DOI: 10.1021/acs.biochem.6b00638 BindingDB Entry DOI: 10.7270/Q2C8284N
					More data for this Ligand-Target Pair
F420-dependent glucose-6-phosphate dehydrogenase [W44A] (Mycobacterium tuberculosis)	BDBM197175 (F420) Show SMILES C[C@H](OP(O)(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)Cn1c2cc(=O)ccc2cc2c1[nH]c(=O)[nH]c2=O)C(=O)N[C@@H](CCC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C29H36N5O18P/c1-12(25(42)31-17(28(46)47)4-6-21(38)30-16(27(44)45)5-7-22(39)40)52-53(49,50)51-11-20(37)23(41)19(36)10-34-18-9-14(35)3-2-13(18)8-15-24(34)32-29(48)33-26(15)43/h2-3,8-9,12,16-17,19-20,23,36-37,41H,4-7,10-11H2,1H3,(H,30,38)(H,31,42)(H,39,40)(H,44,45)(H,46,47)(H,49,50)(H2,32,33,43,48)/t12-,16-,17-,19-,20+,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	120	n/a	n/a	n/a	7.0	n/a
The University of Texas at Arlington					Assay Description Fluorescence spectroscopy was used to determine the G6P and F420 dissociationconstants (Kd) for the FGD wild-type and mutant enzymes. A Spectrosil Qu...				Biochemistry 55: 5566-5577 (2016) Article DOI: 10.1021/acs.biochem.6b00638 BindingDB Entry DOI: 10.7270/Q2C8284N
					More data for this Ligand-Target Pair
F420-dependent glucose-6-phosphate dehydrogenase [E109Q] (Mycobacterium tuberculosis)	BDBM197175 (F420) Show SMILES C[C@H](OP(O)(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)Cn1c2cc(=O)ccc2cc2c1[nH]c(=O)[nH]c2=O)C(=O)N[C@@H](CCC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C29H36N5O18P/c1-12(25(42)31-17(28(46)47)4-6-21(38)30-16(27(44)45)5-7-22(39)40)52-53(49,50)51-11-20(37)23(41)19(36)10-34-18-9-14(35)3-2-13(18)8-15-24(34)32-29(48)33-26(15)43/h2-3,8-9,12,16-17,19-20,23,36-37,41H,4-7,10-11H2,1H3,(H,30,38)(H,31,42)(H,39,40)(H,44,45)(H,46,47)(H,49,50)(H2,32,33,43,48)/t12-,16-,17-,19-,20+,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	500	n/a	n/a	n/a	7.0	n/a
The University of Texas at Arlington					Assay Description Fluorescence spectroscopy was used to determine the G6P and F420 dissociationconstants (Kd) for the FGD wild-type and mutant enzymes. A Spectrosil Qu...				Biochemistry 55: 5566-5577 (2016) Article DOI: 10.1021/acs.biochem.6b00638 BindingDB Entry DOI: 10.7270/Q2C8284N
					More data for this Ligand-Target Pair
F420-dependent glucose-6-phosphate dehydrogenase [W44Y] (Mycobacterium tuberculosis)	BDBM197175 (F420) Show SMILES C[C@H](OP(O)(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)Cn1c2cc(=O)ccc2cc2c1[nH]c(=O)[nH]c2=O)C(=O)N[C@@H](CCC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C29H36N5O18P/c1-12(25(42)31-17(28(46)47)4-6-21(38)30-16(27(44)45)5-7-22(39)40)52-53(49,50)51-11-20(37)23(41)19(36)10-34-18-9-14(35)3-2-13(18)8-15-24(34)32-29(48)33-26(15)43/h2-3,8-9,12,16-17,19-20,23,36-37,41H,4-7,10-11H2,1H3,(H,30,38)(H,31,42)(H,39,40)(H,44,45)(H,46,47)(H,49,50)(H2,32,33,43,48)/t12-,16-,17-,19-,20+,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.17E+3	n/a	n/a	n/a	7.0	n/a
The University of Texas at Arlington					Assay Description Fluorescence spectroscopy was used to determine the G6P and F420 dissociationconstants (Kd) for the FGD wild-type and mutant enzymes. A Spectrosil Qu...				Biochemistry 55: 5566-5577 (2016) Article DOI: 10.1021/acs.biochem.6b00638 BindingDB Entry DOI: 10.7270/Q2C8284N
					More data for this Ligand-Target Pair