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SMILES: Cc1cc(C)n2cc(\C=C/c3ccc4ccccc4n3)nc2n1

InChI Key: InChIKey=VCJQMIGZVTVBKJ-KTKRTIGZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM197731 (US9216986, 2-[(Z)-2-(5,7-Dimethyl-imidazo[1,2-a]py...) Show SMILES Cc1cc(C)n2cc(\C=C/c3ccc4ccccc4n3)nc2n1 Show InChI InChI=1S/C19H16N4/c1-13-11-14(2)23-12-17(22-19(23)20-13)10-9-16-8-7-15-5-3-4-6-18(15)21-16/h3-12H,1-2H3/b10-9-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9801878 (2017) BindingDB Entry DOI: 10.7270/Q26Q20CD
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779] (Homo sapiens (Human))	BDBM197731 (US9216986, 2-[(Z)-2-(5,7-Dimethyl-imidazo[1,2-a]py...) Show SMILES Cc1cc(C)n2cc(\C=C/c3ccc4ccccc4n3)nc2n1 Show InChI InChI=1S/C19H16N4/c1-13-11-14(2)23-12-17(22-19(23)20-13)10-9-16-8-7-15-5-3-4-6-18(15)21-16/h3-12H,1-2H3/b10-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9216986 (2015) BindingDB Entry DOI: 10.7270/Q2Z31XG5
					More data for this Ligand-Target Pair