BDBM197739 US9216986, 6-Fluoro-2-[2-(8-methoxy-5-methyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-ethyl]-quinoline::US9801878, 6-Fluoro-2-[2-(8-methoxy-5-methyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-ethyl]-quinoline

SMILES: COc1ccc(C)n2nc(CCc3ccc4cc(F)ccc4n3)nc12

InChI Key: InChIKey=UWQBRNLTAQDTSL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197739   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM197739 (US9216986, 6-Fluoro-2-[2-(8-methoxy-5-methyl-[1,2,...) Show SMILES COc1ccc(C)n2nc(CCc3ccc4cc(F)ccc4n3)nc12 Show InChI InChI=1S/C19H17FN4O/c1-12-3-9-17(25-2)19-22-18(23-24(12)19)10-7-15-6-4-13-11-14(20)5-8-16(13)21-15/h3-6,8-9,11H,7,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9801878 (2017) BindingDB Entry DOI: 10.7270/Q26Q20CD
					More data for this Ligand-Target Pair
PED10A (Homo sapiens (Human))	BDBM197739 (US9216986, 6-Fluoro-2-[2-(8-methoxy-5-methyl-[1,2,...) Show SMILES COc1ccc(C)n2nc(CCc3ccc4cc(F)ccc4n3)nc12 Show InChI InChI=1S/C19H17FN4O/c1-12-3-9-17(25-2)19-22-18(23-24(12)19)10-7-15-6-4-13-11-14(20)5-8-16(13)21-15/h3-6,8-9,11H,7,10H2,1-2H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9216986 (2015) BindingDB Entry DOI: 10.7270/Q2Z31XG5
					More data for this Ligand-Target Pair